Joe Marks, a seasoned expert in innovation and applied computing for over 30 years, discusses the development and applications of artificial intelligence, including generative AI. He speaks about the application of generative AI in healthcare, such as generating operating room schedules and drafting discharge summaries, but emphasizes the need for human oversight: the “human in the loop.” Joe also touches on the ethical challenges, limitations, and potential future impact of AI on administrative healthcare processes and genomics-based precision medicine.